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Table 2 Antioxidant and immunomodulatory activities of Chinese tonifying herbs

From: Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs

 

aDPPH radical scavenging IC50 (mg/ml)

bImmunomodulatory index in vitro

cImmunomodulatory index ex vivo

Control

 

1.00 ± 0.03

1.00 ± 0.05

Yang herbs

   

Cortex Eucommiae

> 5

0.46 ± 0.02*

1.04 ± 0.09

Fructus Psoraleae

1.0 ± 0.0

1.42 ± 0.02*

1.23 ± 0.01*

Herba Cistanches

1.8 ± 0.0

0.75 ± 0.13

0.95 ± 0.12

Herba Epimedii

1.1 ± 0.1

0.57 ± 0.03*

0.98 ± 0.01

Radix Dipsaci

0.8 ± 0.0

0.42 ± 0.08*

1.02 ± 0.02

Radix Morindae

> 5

2.16 ± 0.10*

1.31 ± 0.04*

Rhizoma Cibotii

0.6 ± 0.0

0.16 ± 0.03*

0.97 ± 0.04

Rhizoma Drynariae

> 5

0.59 ± 0.09*

0.98 ± 0.08

Yin herbs

   

Fructus Ligustri

0.5 ± 0.0

1.73 ± 0.07*

1.80 ± 0.17*

Herba Dendrobii

1.4 ± 0.1

2.54 ± 0.09*

1.59 ± 0.09*

Herba Ecliptae

> 5

1.65 ± 0.02*

1.27 ± 0.12*

Radix Asparagi

> 5

0.70 ± 0.02*

1.24 ± 0.05*

Radix Ophiopogonis

> 5

1.65 ± 0.05*

1.44 ± 0.11*

Radix Oryzae

> 5

0.78 ± 0.13

0.97 ± 0.04

Rhizoma Polygonati

3.5 ± 0.3

1.43 ± 0.09*

1.21 ± 0.06*

Semen Prinsepiae

> 5

1.70 ± 0.03*

1.39 ± 0.11*

  1. aMethanol extracts of tonifying herbs were subjected to the DPPH assay. Values given are means ± S.D., (n = 3). (DPPH scavenging activity was regarded as negligible if the IC50 was > 5 mg/ml).
  2. bSplenocytes isolated from mice were cultured in 96-well microtiter plates in a final volume of 100 μl of culture medium, with the respective methanol extracts added at final concentrations ranging from 15.6–1000 μg/ml. Values given are means ± S.E.M., (n = 4).
  3. cAnimals were pretreated orally with the methanol extracts at a daily dose of 1 g/kg for 3 days. All animals were sacrificed 24 hours post-dosing. Splenocytes isolated from pretreated animals were cultured in microtiter plates in a final volume of 100 μl culture medium. Values given are means ± S.E.M., (n = 3–5).
  4. * Significantly different from the control group (P < 0.05)