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Table 2 Antioxidant and immunomodulatory activities of Chinese tonifying herbs

From: Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs

  aDPPH radical scavenging IC50 (mg/ml) bImmunomodulatory index in vitro cImmunomodulatory index ex vivo
Control   1.00 ± 0.03 1.00 ± 0.05
Yang herbs    
Cortex Eucommiae > 5 0.46 ± 0.02* 1.04 ± 0.09
Fructus Psoraleae 1.0 ± 0.0 1.42 ± 0.02* 1.23 ± 0.01*
Herba Cistanches 1.8 ± 0.0 0.75 ± 0.13 0.95 ± 0.12
Herba Epimedii 1.1 ± 0.1 0.57 ± 0.03* 0.98 ± 0.01
Radix Dipsaci 0.8 ± 0.0 0.42 ± 0.08* 1.02 ± 0.02
Radix Morindae > 5 2.16 ± 0.10* 1.31 ± 0.04*
Rhizoma Cibotii 0.6 ± 0.0 0.16 ± 0.03* 0.97 ± 0.04
Rhizoma Drynariae > 5 0.59 ± 0.09* 0.98 ± 0.08
Yin herbs    
Fructus Ligustri 0.5 ± 0.0 1.73 ± 0.07* 1.80 ± 0.17*
Herba Dendrobii 1.4 ± 0.1 2.54 ± 0.09* 1.59 ± 0.09*
Herba Ecliptae > 5 1.65 ± 0.02* 1.27 ± 0.12*
Radix Asparagi > 5 0.70 ± 0.02* 1.24 ± 0.05*
Radix Ophiopogonis > 5 1.65 ± 0.05* 1.44 ± 0.11*
Radix Oryzae > 5 0.78 ± 0.13 0.97 ± 0.04
Rhizoma Polygonati 3.5 ± 0.3 1.43 ± 0.09* 1.21 ± 0.06*
Semen Prinsepiae > 5 1.70 ± 0.03* 1.39 ± 0.11*
  1. aMethanol extracts of tonifying herbs were subjected to the DPPH assay. Values given are means ± S.D., (n = 3). (DPPH scavenging activity was regarded as negligible if the IC50 was > 5 mg/ml).
  2. bSplenocytes isolated from mice were cultured in 96-well microtiter plates in a final volume of 100 μl of culture medium, with the respective methanol extracts added at final concentrations ranging from 15.6–1000 μg/ml. Values given are means ± S.E.M., (n = 4).
  3. cAnimals were pretreated orally with the methanol extracts at a daily dose of 1 g/kg for 3 days. All animals were sacrificed 24 hours post-dosing. Splenocytes isolated from pretreated animals were cultured in microtiter plates in a final volume of 100 μl culture medium. Values given are means ± S.E.M., (n = 3–5).
  4. * Significantly different from the control group (P < 0.05)