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Table 5 Immunomodulatory activities of Yin tonifying herbs

From: Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs

HERBS

IMMUNOMODULATORY ACTIVITIES

REFS

Fructus Ligustri

Methanolic extract or petroleum ether fraction enhanced Con A-stimulated proliferation of mouse splenocytes in vitro and ex vivo

[4,36]

Radix Asparagi

Water extract inhibited TNF-α secretion by suppressing IL-2 secretion from astrocytes

[39]

Radix Ophiopogonis

Water extract inhibited xylene-induced ear swelling and carrageenan-induced paw edema in mice Active ingredients (ruscogenin and ophiopogonin D) decreased zymosan-induced adhesion of HL60 cells to ECV304 cells

[40]

Herba Dendrobii

Active ingredients (sesquiterpenes) showed a co-mitogenic effect on Con A and lipopolysaccharide-stimulated mouse splenocytes

[41,42]

Radix Oryza

Ethanolic extract of black rice (the fruit of Oryza sativa) decreased the extents of airway inflammation and hyper-response in OVA-immunized and aerolized OVA-challenged mice

Ethanolic extract of black rice decreased various cytokine levels in the supernatant of cultured splenocytes and suppressed the plasma levels of OVA-specific IgG and total IgE in OVA-immunized and challenged mice

[43]