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Table 1 Fifty percent inhibition concentrations (IC50) and relative resistance of curcumin and cantharidin in sensitive and multidrug-resistant CEM leukemia tumor cell lines [16]

From: Molecular biology of cantharidin in cancer cells

  Curcumin Cantharidin
Growth inhibition assay:
CCRF-CEM 30 μM 20 μM
CEM/ADR5000 28 μM 17 μM
Relative resistance 0.9 0.9
MTT-Assay:
CCRF-CEM >13.5 μM 1.9 μM
CEM/VBL100 >13.5 μM 1.4 μM
Relative resistance: n.d. 1.4
CEM/E1000 13.5 μM 0.76 μM
Relative resistance n.d. 0.4
  1. n.d.: not determined