Effects of the five Chinese medicine decoctions on histological changes of liver. (a) Hematoxylin - eosin (H&E) ×200. (A) Control rats (B) 2-week DMN fibrotic rats (C) DMN + water cirrhotic rats (D) DMN + YCHT rats (E) DMN + XYXT rats (F) DMN + HQT rats (G) DMN + YGJ rats (H) DMN + XCHT rats. (b) Sirius red stain ×100. (A) Collagen was scarcely observed. (B) Collagen was stretched from portal to lobular area. (C) Portal and lobular bridging fibrosis, and cirrhotic nodule formation were observed. (D) Fibrosis significantly decreased. (E), (F), (G) and (H) Changes in collagen deposition were observed.