Skip to main content

Advertisement

Table 2 Effects of five Chinese medicine decoctions on liver hydroxyproline (Hyp) content in DMN-induced liver fibrosis of rats

From: Effects of Yinchenhao Tang and related decoctions on DMN-induced cirrhosis/fibrosis in rats

Group Group size (n) Hyp content μg/g mean (SD) Fibrotic grade* 95% CI of U**
0 1 2 3 4
Control 10 179.36(9.90)▲▲ 10 0 0 0 0 (-0.110 to 0.228)▲▲
2-week DMN 6 289.06 (26.95)▲▲ 0 0 4 2 0 (0.051 to 0.486)▲▲
DMN + water 12 641.71 (54.22) 0 0 0 3 9 (0.586 to 0.894)
DMN + YCHT 12 434.16 (25.39) 0 0 5 6 1 (0.226 to 0.548)
DMN + XYXT 12 586.91 (37.53) 0 0 0 5 7 (0.522 to 0.829)
DMN + HQT 12 559.04 (47.06) 0 0 0 8 4 (0.580 to 0.734)
DMN + YGJ 12 647.17 (64.73) 0 0 1 6 5 (0.435 to 0.743)
DMN + XCHT 10 636.35 (48.53) 0 0 1 7 2 (0.333 to 0.671)
  1. *: grade 0: normal; grade 1: very slight; grade 2: slight; grade 3: moderate; grade 4: severe. Data are expressed as numbers of animals with each fibrotic grade.
  2. **: 95% confidence interval of the U values obtained from ridit analysis
  3. P < 0.05 ▲▲P < 0.01 (vs DMN+ water)
  4. P < 0.05 P < 0.01 (vs 2-week DMN)
  5. YCHT: Yinchenhao Tang
  6. XYXT: Xiayuxue Tang
  7. HQT:Huangqi Tang
  8. YGJ: Yiguang Jian
  9. XCHT: Xiaochaihu Tang
  10. Results are expressed as mean (SD).