Anti-inflammatory effects of KHU14 on animal models of acute inflammation. (A) Ear edema in mice (n = 10). (B) Paw edema in rats (n = 8). (C) Capillary permeability test (n = 15). The mice and rats were orally fed with KHU14 (400 mg/kg of body weight) and celecoxib (100 mg/kg of body weight). The control group received 0.5% CMC orally. NS: not significant.