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Table 1 Anti-inflammatory activity data of curcumin derivatives

From: Recent advances in the investigation of curcuminoids

Compound

R1

R2

R3

R4

ED50 (mg/kg)

2

H

OCH3

OH

H

38 ± 4

3

H

H

OH

H

73 ± 5

12

H

H

H

H

NA

13

H

OCH3

H

H

NA

14

H

OCH3

OCH3

OCH3

NA

15

H

CH3

OH

CH3

13 ± 2

16

H

C2H5

OH

C2H5

22 ± 6

17

H

i-C3H7

OH

i-C3H7

58 ± 21

18

OCH3

H

H

H

NA

19

H

H

Cl

H

NA

20

H

H

OCH3

H

82 ± 7

21

H

H

CH3

H

80 ± 18

22

H

OCH3

OCH3

H

50 ± 22

23

H

t-C4H9

OH

t-C4H9

NA

24

H

OCH3

OH

OCH3

28 ± 5

  1. NA: not active
  2. ED50 values are expressed as 'means ± standard deviations'.
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Chinese Medicine

ISSN: 1749-8546

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