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Table 4 Cytotoxic activity data of curcumin derivatives against PC-3 and LNCaP prostate cancer cell lines

From: Recent advances in the investigation of curcuminoids

Compound

R1

R2

PC-3 IC50 (μM)*

LNCaP IC50 (μM)*

2

H

H

7.7

3.8

38

CH3

H

1.1

1.3

39

H

CH2CH2COOEt

5.1

1.5

40

CH3

CH=CHCOOEt

1.0

0.2

  1. IC50 values are mean concentrations that inhibit cell growth by 50% (variation between replicates was less than 5%).
  2. IC50 values are expressed as 'means'.
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Chinese Medicine

ISSN: 1749-8546

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