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Table 1 Quality control interests and disadvantages of chemical markers

From: Chemical markers for the quality control of herbal medicines: an overview

Category Quality control interests Disadvantages
Therapeutic components Indicating efficacy Not always obtained
Toxic components Safety assurance Need extensive toxicological studies
Bioactive components May indicate efficacy Not always indicate the overall quality
Main components Stability and consistency test Not always indicate the overall quality
Characteristic components Qualitative identification Not always obtained
Synergistic components Revealing synergistic actions of multi-components Need extensive pharmacological studies
Correlative components Prediction of storage period, extraction methods and sometimes collection site etc. Need extensive phytochemical studies
General components used together with fingerprint spectrum Indicating overall quality when used together with fingerprint spectrum Mass data analysis