Percentiles | ||||||
---|---|---|---|---|---|---|
Group (n = 10) | Dose (mg/kg) | Mean | SD | 25th | 50th (median) | 75th |
Bax | ||||||
Control | - | 13633 | 2531 | 11244 | 13712 | 15634 |
Acetylshikonin | 2 × 6 | 48678 | 2534 | 46432 | 48519*** | 51406 |
1 × 6 | 28502 | 5064 | 23628 | 30232*** | 33082 | |
0.5 × 6 | 21844 | 4882 | 16476 | 22988** | 26209 | |
bcl-2 | ||||||
Control | - | 19859 | 2822 | 17076 | 20065 | 22292 |
Acetylshikonin | 2 × 6 | 8126 | 1115 | 7267 | 7926*** | 8596 |
1 × 6 | 11171 | 1459 | 9916 | 10814*** | 12478 | |
0.5 × 6 | 15652 | 1724 | 14447 | 15234** | 16742 | |
Bax/bcl-2 | ||||||
Control | - | 0.70 | 0.17 | 0.58 | 0.74 | 0.79 |
Acetylshikonin | 2 × 6 | 6.11 | 0.92 | 5.54 | 6.05*** | 6.26 |
1 × 6 | 2.56 | 0.36 | 2.34 | 2.47*** | 2.77 | |
0.5 × 6 | 1.41 | 0.32 | 1.14 | 1.29** | 1.77 | |
Caspase-3 | ||||||
Control | - | 12746 | 3155 | 10359 | 12019 | 13714 |
Acetylshikonin | 2 × 6 | 31618 | 3155 | 29396 | 31226*** | 33530 |
1 × 6 | 22653 | 4647 | 18898 | 21756*** | 25119 | |
0.5 × 6 | 13582 | 3737 | 10009 | 13186 | 17705 |