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Table 1 Effects of ASI on FS (%)

From: Effects of Astragaloside IV on heart failure in rats

Group Dose (mg/kg/day) Normal Before treatment After treatment
1 week 2 weeks
Sham - 73.0 ± 5.7 68.8 ± 6.5 70.9 ± 3.4 66.1 ± 8.0
Model - 68.8 ± 10.1 (0.2193) 30.8 ± 5.0+++ 26.1 ± 6.6+++ 22.7 ± 7.6+++
ASI 0.1 72.8 ± 3.6 (0.2417) 28.9 ± 4.6 (0.4213) 34.2 ± 7.5* (0.0163) 27.4 ± 7.8 (0.2620)
ASI 0.3 72.1 ± 9.6 (0.3329) 28.8 ± 6.9 (0.3973) 41.5 ± 11.3*** 28.8 ± 8.9 (0.1474)
ASI 1.0 68.4 ± 6.7 (0.9061) 31.7 ± 2.5 (0.7024) 42.9 ± 7.7*** 35.8 ± 13.2** (0.0028)
Quinapril 1.0 70.1 ± 7.5 (0.7016) 30.2 ± 4.7 (0.7989) 42.4 ± 4.7*** 31.4 ± 8.8* (0.0411)
  1. Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significances over the model group (comparison of group means after ANOVA). No statistical significance between ASI (1.0 mg/kg/day) and Quinapril treatments. Exact P values are available in brackets.