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Table 2 Effects of ASI on +dp/dt and -dp/dt

From: Effects of Astragaloside IV on heart failure in rats

Group Dose (mg/kg/day) +dp/dt (mmHg/s) -dp/dt (mmHg/s)
Sham - 3454 ± 774 3706 ± 517
Model - 2216 ± 800+++ 1922 ± 672+++
ASI 0.1 2459 ± 524 (0.3679) 2362 ± 610 (0.0710)
ASI 0.3 2838 ± 420* (0.0246) 2699 ± 425** (0.0021)
ASI 1.0 3066 ± 630** (0.0027) 2776 ± 578***
Quinapril 1.0 2847 ± 251* (0.0228) 2601 ± 310** (0.0065)
  1. Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significance over the model group (comparison of group means after ANOVA). No significance between ASI (1.0 mg/kg/day) and Quinapril treatments. Exact P values are available in brackets.