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Table 2 Effects of ASI on +dp/dt and -dp/dt

From: Effects of Astragaloside IV on heart failure in rats

Group

Dose (mg/kg/day)

+dp/dt (mmHg/s)

-dp/dt (mmHg/s)

Sham

-

3454 ± 774

3706 ± 517

Model

-

2216 ± 800+++

1922 ± 672+++

ASI

0.1

2459 ± 524 (0.3679)

2362 ± 610 (0.0710)

ASI

0.3

2838 ± 420* (0.0246)

2699 ± 425** (0.0021)

ASI

1.0

3066 ± 630** (0.0027)

2776 ± 578***

Quinapril

1.0

2847 ± 251* (0.0228)

2601 ± 310** (0.0065)

  1. Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significance over the model group (comparison of group means after ANOVA). No significance between ASI (1.0 mg/kg/day) and Quinapril treatments. Exact P values are available in brackets.
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Chinese Medicine

ISSN: 1749-8546

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