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Table 3 Effects of ASI on LV dimensions

From: Effects of Astragaloside IV on heart failure in rats

      After treatment
Group Dose (mg/kg/day) Normal Before treatment 1 week 2 weeks
  Sham - 4.8 ± 1.0 5.2 ± 1.3 5.2 ± 0.7 5.2 ± 0.9
  Model - 4.8 ± 1.2 (0.9549) 7.0 ± 1.1++ (0.0046) 7.5 ± 0.4+++ 7.1 ± 0.7+++
LVIDd (mm) ASI 0.1 5.0 ± 0.8 (0.6785) 6.9 ± 1.2 (0.9603) 6.9 ± 1.0 (0.1601) 6.5 ± 1.1 (0.1109)
  ASI 0.3 4.5 ± 1.2 (0.5850) 6.2 ± 1.9 (0.1946) 6.7 ± 1.7 (0.0547) 6.0 ± 0.9** (0.0057)
  ASI 1.0 4.7 ± 1.5 (0.7629) 6.4 ± 1.3 (0.3389) 6.5 ± 0.8* (0.0193) 6.0 ± 0.5**$ (0.0046)
  Quinapril 1.0 5.1 ± 1.2 (0.6512) 6.6 ± 1.1 (0.5964) 6.7 ± 0.8 (0.0574) 6.7 ± 0.9 (0.3837)
  Sham - 1.3 ± 0.4 1.6 ± 0.4 1.5 ± 0.3 1.8 ± 0.5
  Model - 1.5 ± 0.5 (0.4268) 4.8 ± 1+++ 5.6 ± 0.8+++ 5.5 ± 0.8+++
LVIDs (mm) ASI 0.1 1.4 ± 0.3 (0.8811) 4.9 ± 0.9 (0.8356) 4.5 ± 0.9* (0.0112) 4.7 ± 0.9* (0.0447)
  ASI 0.3 1.2 ± 0.4 (0.1827) 4.5 ± 1.6 (0.3955) 4.0 ± 1.6*** 4.3 ± 1.0** (0.0027)
  ASI 1.0 1.4 ± 0.4 (0.6903) 4.4 ± 0.8 (0.3353) 3.7 ± 0.7*** 3.8 ± 1.0***$
  Quinapril 1.0 1.6 ± 0.7 (0.5180) 4.6 ± 0.7 (0.6125) 3.9 ± 0.6*** 4.8 ± 0.8 (0.0595)
  1. Note: Values are mean ± SD in each group (n = 10). ++P < 0.01, +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significance over the model group (comparison of group means after ANOVA). $P < 0.05: statistical significance between ASI (1.0 mg/kg/day) and Quinapril treatments (comparison of group means after ANOVA). Exact P values are available in brackets.