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Table 4 Effects of ASI on LVSP, LVEDP and wall stress

From: Effects of Astragaloside IV on heart failure in rats

Group

Dose (mg/kg/day)

LVSP (mmHg)

LVEDP (mmHg)

Wall stress (g/cm2)

Sham

-

111.8 ± 12.1

-0.7 ± 5.8

47.7 ± 17.6

Model

-

88.5 ± 14.0+++

13.9 ± 5.4+++

125.9 ± 28.0+++

ASI

0.1

101.4 ± 18.5* (0.0367)

10.6 ± 3.6 (0.1629)

120.4 ± 31.9 (0.6563)

ASI

0.3

101.6 ± 9.0* (0.0340)

9.8 ± 5.3 (0.0848)

108.3 ± 24.5 (0.1613)

ASI

1.0

100.2 ± 8.4$$ (0.0571)

6.2 ± 4.2** (0.0018)

97.9 ± 29.8* (0.0283)

Quinapril

1.0

84.0 ± 15.5 (0.4566)

3.5 ± 6.3***

95.1 ± 31.7* (0.0167)

  1. Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significance over the model group (comparison of group means after ANOVA). $$P < 0.01: statistical significance between ASI (1.0 mg/kg/day) and Quinapril treatments (comparison of group means after ANOVA). Exact P values are available in brackets.
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Chinese Medicine

ISSN: 1749-8546

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