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Table 6 Effects of ASI on myocardial apoptosis and Bax

From: Effects of Astragaloside IV on heart failure in rats

Group Dose (mg/kg/day) Apoptotic cell Bax protein
Sham - 3.0 ± 2.2 1.6 ± 1.3
Model - 54.0 ± 10.2+++ 30.2 ± 8.8+++
ASI 0.1 37.8 ± 8.6*** 24.3 ± 7.1*
ASI 0.3 17.0 ± 8.4*** 8.4 ± 5.3***
ASI 1.0 8.0 ± 5.6*** 7.3 ± 3.4***
Quinapril 1.0 10.4 ± 6.4*** 12.0 ± 5.5***
  1. Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, ***P < 0.001: statistical significance over the model group (comparison of group means after ANOVA). No statistical significance between ASI (1.0 mg/kg/day) and Quinapril treatments (comparison of group means after ANOVA).