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Table 1 Calibration curves of the three Panax notoginseng saponins in beagle dog plasma

From: Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

Analyte

Standard curves (linear)

P

r 2

Test range (ng/mL)

Limit of quantification (ng/mL)

NotoginsenosideR1

Y = 0.0011X+0.0004

0.003

0.9967

2.64--264

0.50

Ginsenoside Rg1

Y = 0.0009X+0.0007

0.004

0.9941

3.60--360

0.82

Ginsenoside Rb1

Y = 0.0016X+ 0.0283

0.004

0.9912

18.7--1870

1.10

  1. Note: Y, peak area ratio (analyte/internal standard); X, concentration of analyte in plasma (ng/mL)