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Table 2 Intra- and interday variability for the assay of the three Panax notoginseng saponins in beagle dog plasma (n = 6)

From: Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

Spiked conc. (ng/mL) Intraday Interday
Measured conc. (ng/mL) RSD (%) a Accuracy (%) b Measured conc. (ng/mL) RSD (%) Accuracy (%)
Notoginsenoside R1       
2.8 2.8 1.27 100.0 2.68 1.49 95.71
14 13.9 0.76 99.29 12.89 9.62 92.1
140 148 8.22 105.7 131.67 10.11 105.7
Ginsenoside Rg1       
3.8 3.6 5.13 94.7 3.96 11.96 104.2
19 17.6 3.65 92.6 18.3 8.95 96.3
190 197.3 6.59 103.8 193.7 7.66 101.7
Ginsenoside Rb1       
18 18.1 3.07 100.6 17.6 5.36 96.11
180 165.3 2.73 91.83 179.7 5.05 99.50
900 912.67 3.90 101.3 871.3 2.38 96.87
  1. Note: aRelative standard deviation; bAccuracy (%) = [1--(nominal concentration -- mean of measured concentration)/nominal concentration] × 100