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Table 3 Recovery of the three Panax notoginseng saponins from beagle dog plasma (n = 4)

From: Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

Analyte Spiked conc. (ng/mL) Recovery (%)a, b RSD (%)c
Notoginsenoside R1 2.8 96.0 ± 6.72 6.99
14 104.0 ± 7.71 7.41
140 102.3 ± 7.82 7.82
Ginsenoside Rg1 3.8 99.9 ± 6.89 6.90
19 102.4 ± 6.73 6.57
190 98.96 ± 8.06 8.14
Ginsenoside Rb1 18 102.6 ± 9.85 9.60
180 101.1 ± 10.26 9.14
900 105.0 ± 8.32 7.92
  1. Note: aRecovery (%) = [1 -- (spiked concentration -- measured concentration)/spiked concentration] × 100; bValues are the mean ± SD (n = 4); c Relative standard deviation