From: Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)
Name | Bioactivities | References |
---|---|---|
Derivatives of 12-hydroxy-14-dehydroandrographolide | TNF-α and IL-6 secretion in mouse macrophages | [13] |
3,19-O-diacetylanhydroandrographolide | NF-κB-dependent trans-activation in the RAW264.7 cells | [17] |
DRF3188 |
block MCF-7 cell cycle at the G0/G1 phase cell cycle inhibitor, p27 the levels of CDK4 | [46] |
14-Alphal-lipoyl andrographolide | against H9N2, H5N1 and H1N1 viruses to reduced the death rate, prolonged life and inhibited lung consolidation and viral titers | [83] |
14-Glycinyl andrographolide hydrochloride | reduced virulence factor production | [84] |
SRJ23 | G1 arrest and apoptosis in MCF-7 and HCT-116 | [62] |
SRJ09 | G1 arrest and apoptosis in MCF-7 and HCT-116 | [62] |
3,19-isopropylideneandrographolide | cyotoxicity against MCF-7 and HCT-116 | [47] |
14-acetyl-3,19-isopropylidene andrographolide | cyotoxicity against MCF-7 and HCT-116 | [47] |