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Table 1 In vitro anti-RSV activity of compounds I-IV (n = 3)

From: Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen)

Compound CC50(μM) a IC50(μM) b SI
I 29.9 (3.2) - -
II 106.1 (5.9) 9.6 (0.7) 11.0
III 145.3 (3.1) 6.6 (1.1) 21.9
IV 161.5 (5.7) 10.2 (0.8) 15.8
Ribavirin 256.1 (3.2) 11.9 (0.2) 21.6
  1. a CC50 is the concentration of sample with half maximal inhibition on the growth and survival of HEp-2 cells; data are expressed as mean (SD).
  2. b IC50 is the concentration that reduced 50% of CPE in respect to virus control; data are expressed as mean (SD).
  3. -: The sample did not show anti-RSV effect at its NMCC.