Skip to main content

Table 4 Effects of ethyl acetate root extract of Desmodium gangeticu m on TBARS, catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) in the tissue homogenate of isolated rat hearts

From: Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts

Group

TBARS (μM/g wet tissue)

Catalase (μM of H2O2 consumed/min/g protein)

SOD (U/mg protein)#

GPx (μg of GSH consumed/min/g protein)

Mn SOD

Cu-Zn SOD

Normal control

1

6.1 ± 0.2

7617 ± 441

8.1 ± 0.62

50.2 ± 4.1

1859 ± 181

Ischemia reperfusion control

2.1

7.9 ± 0.6*

4 087 ± 246*

5.1 ± 0.52*

30.3 ± 3.5*

1228 ± 142*

2.2

7.5 ± 0.5*

5176 ± 372*

6.1 ± 0.54*

34.1 ± 3.2*

1117 ± 114*

2.3

7.1 ± 0.5*

5208 ± 316*

5.6 ± 0.57*

33.8 ± 3.8*

1216 ± 116*

Drug treated

3.1

5.9 ± 0.3

7856 ± 447

8.0 ± 0.71

50.1 ± 4.3

1855 ± 178

3.2

5.9 ± 0.3

7573 ± 433

8.0 ± 0.78

51.0 ± 4.9

1804 ± 183

3.3

4.8 ± 0.2*

6176 ± 455*

7.1 ± 0.62*

44.3 ± 4.1

1572 ± 176*

  1. #SOD unit: One unit is defined as the enzyme concentration required to inhibit the optical density (at 560 nm) produced by 50% of chromogen 50% in 1 minute.
  2. Values are mean ± SD in each group (n = 6). Significantly differing values (from normal control group) are marked with an asterisk (P < 0.05).