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Table 7 The most significant cell component group of functional annotation by DAVID and GOTM of the differentially expressed proteins of the hippocampus and cerebellum by 2D gel electrophoresis and mass spectrometric analysis with a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF)/TOF tandem mass spectrometer

From: Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke

Method

Brain region

Term

P value

Benjamini *

Proteins

DAVID

Hippocampus

Mitochondrion

0.0000185

0.01497

NP_036629, NP_112287 *, NP_071565 *, NP_001006973, NP_001006971, NP_001008888.

Cerebellum

Mitochondrial inner membrane

0.0000317

0.02553

NP_075581, NP_001006971, NP_036702, NP_114039, NP_037309.

GOTM

Hippocampus

Mitochondrial membrane part

0.000000279

Nil

NP_001006973, NP_071565 *, NP_001008888, NP_001006971.

Cerebellum

Mitochondrial inner membrane

0.0016

Nil

NP_036702, NP_075581, NP_001006971, NP_037309.

  1. * P value by Benjamini correction in DAVID analysis. Other multiple testing correction techniques, Bonferroni and FDR, as provided by DAVID gave the same p values