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Table 1 Detection of aristolochic acid (AA) in study drug and other brand products in the market

From: Is Duhuo Jisheng Tang containing Xixin safe? A four-week safety study

Chinese herbal products Sample no. Contents (μg/g)
AA-I a AA-II a
   DJT (study drug) 1 (--) (--)
  25-fold concentration (--) (--)
Other brand products bought in the open market
   DJT (brand 1b) 2 (--) (--)
  16.7-fold concentrationc (--) (--)
   DJT (brand 2) 3 (--) (--)
  25-fold concentration (--) (--)
   DJT (brand 3) 4 (--) (--)
  10-fold concentrationc (--) (--)
   Xixin (brand 1b) 5 (--) (--)
  25-fold concentration 6.64 (--)
   Xixin (brand 2) 6 (--) (--)
  25-fold concentration 6.77 (--)
   Xixin (brand 3) 7 (--) (--)
  25-fold concentration 9.95 (--)
  1. Notes:
  2. a The detection limit of aristolochic acid I (AA-I) and aristolochic acid II (AAII) is 2.0 ng/ml
  3. bBrand 1 products (samples nos. 2 and 5) were also produced by Sun Ten Pharmaceutical Company (Taiwan), but they were directly purchased from the market.
  4. cSamples nos. 2 and 4 could only be concentrated up to less than 25-fold during the test procedure.
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Chinese Medicine

ISSN: 1749-8546

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