EBE inhibited 6-OHDA-induced decrease of total distance of movement in zebrafish. Quantification of the swimming parameter of zebrafish: 4 dpf wild type zebrafish larvae were treated with 6-OHDA (250 μM) and EBE (25 and 50 μg/mL) for three days. The locomotor activity of zebrafish was assessed at seven dpf. All results were expressed as total distance of movement traveled by the larvae, + P = 0.032 versus control group (without 6-OHDA treatment); * P = 0.041, ** P = 0.007 versus 6-OHDA-treated group. All experiments were repeated 3 times.