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Table 1 Randomized trials on herbal medicine for eczema

From: Chinese herbal medicine research in eczema treatment

Population Design Outcome Adverse effects Validity Remarks  
Pediatric Randomized, double-blind, placebo-controlled, crossover Clinical only Nil Not intention-to-treat due to dropouts, no quality of life measurement Efficacy not concurred with [11] [25]
Adults Randomized, double-blind, placebo-controlled, crossover Clinical only Nil Not intention-to-treat due to dropouts, no quality of life measurement Efficacy not concurred with [11] [13, 49]
Pediatric + Adults Randomized, double-blind, placebo-controlled, crossover Clinical only Minor Intention-to-treat, no dropouts, no quality of life measurement No effects [11]
Pediatric Randomized, double-blind, placebo-controlled Clinical + quality of life + oral antihistamine and topical steroid-sparing Minor Intention-to-treat, no dropouts, quality of life + oral antihistamine and topical steroid usage sparing Improved quality of life and steroid-sparing [30]
Adults Randomized to 4 groups, saline as control Poorly defined total effective rate and cured rate Nil Apparently no dropouts, but very small subgroups sizes, no quality of life measurement Effective, difficult to assess efficacy [31]
Adults Randomized, double-blind, placebo-controlled Clinical + topical steroid and tacrolimus-sparing Minor Not intention-to-treat due to dropouts, no quality of life measurement Topical steroid and tacrolimus-sparing only [32]