Skip to main content
Figure 2 | Chinese Medicine

Figure 2

From: Neuroprotective effects of ginsenosides Rh1 and Rg2 on neuronal cells

Figure 2

Figures showing the effect of ginsenoside treatments on SH-SY5Y cells against 6-OHDA toxicity a. Six-hydroxydopamine toxicity on SH-SY5Y cells. The percentage of cell death (cytotoxicity) after 24 hours of exposure to different concentrations of 6-OHDA. Values are presented as mean ± SD (n = 3). (Welch's t-test, ** P = 0.010, ***P < 0.001, vs. control). Negative percentage is considered to be zero percentage as it is resulted by calculation of the LDH assay formula. b. Ginsenosides toxicity on SH-SY5Y cells. The percentage of cell death (cytotoxicity) after 24 hours of exposure to different concentrations of ginsenosides Rh1 and Rg2 Values are presented as mean ± SD (n = 3). The cytotoxicity of ginsenoside-treated groups and the control group was not significantly different (one way ANOVA, P = 0.110). c. Effect of ginsenoside pretreatment on 40 μM 6-OHDA toxicity on SH-SY5Y cells. The percentage of cell death (cytotoxicity) after 24 hours of pretreatment of ginsenosides Rh1 and Rg2 (10 μM and 20 μM) followed by 24 hours co-treatment with ginsenosides together with 40 μM 6-OHDA. Values are presented as mean ± SD (n = 3). The cytotoxicity of ginsenoside-pretreated groups were not significantly different from that of the un-pretreated group (one way ANOVA, P = 0.184). d. Effect of ginsenoside pretreatment on 60 μM 6-OHDA toxicity on SH-SY5Y cells. The percentage of cell death (cytotoxicity) after 24 hours of pretreatment of ginsenosides Rh1 and Rg2 (10 μM and 20 μM) followed by 24 hours co-treatment with ginsenosides together with 60 μM 6-OHDA. Values are presented as mean ± SD (n = 3). (Welch's t-test, *P < 0.05, ** P < 0.01, vs. un-pretreated group. 10 μM Rh1: P = 0.022; 10 μM Rg2: P = 0.002; 20 μM Rg2: P = 0.036).

Back to article page