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Table 3 Similarity between descriptions of Chinese medicine patterns and target-organs damage

From: Zangfu zheng (patterns) are associated with clinical manifestations of zang shang (target-organ damage) in arterial hypertension

  Patterns
Target-organs damage Liver-fire blazing upwards (n = 11) Kidney-yin deficiency and Liver-yang rising (n = 13) Obstruction of phlegm and dampness of Heart/Liver/ Gallbladder (n = 10) Qi and blood deficiency leading to Liver-yang rising (n = 7) Kidney-yin/yang deficiency (n = 11)
CVD (n = 19) 0.15* [0.19; 0.58] 0.23 [0.19; 0.69] 0.26 [0.17; 0.70] 0.30 [0.15; 0.86] 0.15* [0.19; 0.73]
HD (n = 7) 0.12* [0.13; 0.86] 0.11 [0.11; 0.86] 0.13 [0.13; 0.86] 0.00* [0.07; 0.86] 0.06* [0.12; 0.86]
KD (n = 11) 0.16 [0.16; 0.72] 0.14 [0.14; 0.73] 0.11* [0.16; 0.70] 0.06* [0.12; 0.86] 0.22 [0.11; 0.73]
  1. Jaccard coefficient of similarity between manifestations of patterns and target-organs damage calculated from ZFHD and TODD datasets.
  2. * Values significantly lower than expected at random, P < 0.05. All other values not different to those expected at random were left unmarked. Values in brackets represent critical values of S J with a probability level of P < 0.05 considering the total number of manifestations present in either of the two patterns being compared and the minimum quantity of manifestations between patterns and target-organs. CVD: cerebrovascular and eye disease; HD: heart disease; KD: kidney disease.