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Table 2 Herbs or herbal compounds that suppress the production of inflammatory mediators and transcription factors activated by cerebral ischemia

From: Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia

Targeted molecules Herb or compound
Inflammatory meciators  
   Cytokines  
IL-1β andrographolide [30], paeonol [11],Sophora japonica [13],Panax Notoginseng saponins [28], apocynin [20], Scutellaria baicalensis flavonoid [54]
TNF-α andrographolide [30], puerarin [32], wogonin [34]
   NO  
iNOS ferulic acid [38], puerarin [32], tetramethylpyrazine [40], wogonin [34], Panax Notoginseng [15]
   ROS Salviae Miltiorrhiza[41], 4-hydroxybenzyl alcohol [48], Angelica sinensis [51], tanshinone IIA [45]
MPO ferulic acid [26], tetramethylpyrazine [52], Anemarrhena asphodeloides [53], Panax Notoginseng saponins [22]
SOD shikonin [57], paeonol [29], emodin-8-O-β-D-glucoside [58], Zizyphus jujube [16], Scutellaria baicalensis flavonoid [54]
CAT Scutellaria baicalensis isoflavoid [54], shikonin [57]
GSH shikonin [57]
OH· tetramethylpyrazine [40]
NADPH Apocinin [20]
   MMP quercetin [62], Panax Notoginseng saponins [64]
Transcription factors  
   NF-κB andrographolide [30], oxymatrine [81], feulic acid [26], paeoniflorin [82], wogonin [80],Panax Notoginseng [15], apocynin [20]
   P38 Oxymatrine [73], ferulic acid [38]