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Figure 2 | Chinese Medicine

Figure 2

From: Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain

Figure 2

Effects of CTS administration on elevated plus maze performance of SAMP8 with and without ischemic insult. The 20-week-old SAMP8 received sham operation or transient occlusion of common carotid arteries (T2VO) for 15 minutes on day 0 and then received oral administration of water (vehicle) or 750 mg/kg CTS once daily during an experimental period. The elevated plus maze test was conducted on days 17 and 18 after ischemic operation. Each datum represents the mean ± SD (9-10 mice per group). The proportion of time spent in open arms (A) and the number of total arm entries (B) were calculated. The data are expressed as the mean ± SD ###P < 0.001 vs. vehicle-treated SAMR1 group (t-test). ***P < 0.001 vs. vehicle-treated sham- or T2VO-SAMP8 groups (two-way ANOVA).

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Chinese Medicine

ISSN: 1749-8546

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