Figure 6From: Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brainEffects of CTS on expression levels of p-NMDAR1, NMDAR1, p-CaMKII, CaMKIIα, p-CREB, CREB, and GAPDH in the cerebral cortex of SAMP8 with and without ischemic insult. Typical photos indicating the expression levels of each factor in the cerebral cortex of vehicle-treated SAMR1 control (lane 1), vehicle-treated sham-SAMP8 (lane 2), CTS (750 mg/kg/day)-treated sham-SAMP8 (lane 3), vehicle-treated T2VO-SAMP8 (lane 4), and CTS-treated T2VO-SAMP8 group (lane 5). After completing the behavioral studies, the animals were decapitated and proteins were extracted from the cerebral cortices in each animal group.Back to article page