Figure 7

Quantitative comparisons of CTS-induced changes in expression levels of p-NMDAR1, NMDAR1, p-CaMKII, CaMKIIα, p-CREB, CREB, and GAPDH in the cerebral cortex of SAMP8 with and without ischemic insult. The data are expressed as the percentage of the value obtained from naïve control SAMR1 mice. Each data column represents the mean ± SD obtained from 4-5 brain samples. ^#P < 0.05 or ^##P < 0.01 vs. compared with vehicle-treated SAMR1 group (t-test). ***P < 0.001, **P < 0.01 vs. respective vehicle-treated sham- or T2VO-SAMP8 group (two-way ANOVA).