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Figure 8 | Chinese Medicine

Figure 8

From: Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain

Figure 8

Effects of CTS on BDNF mRNA and protein expression in the cerebral cortex. After completing the behavioral studies, we decapitated the animals and prepared the protein and total RNA from the cerebral cortices. Real-time PCR analysis of BDNF mRNA (A) and BDNF protein (B) expression in vehicle-treated SAMR1 (lane 1) and vehicle-treated sham-SAMP8 (lane 2), CTS (750 mg/kg/day)-treated sham-SAMP8 (lane 3), vehicle-treated T2VO-SAMP8 (lane 4), and CTS-treated T2VO-SAMP8 (lane 5). Each data column represents the mean ± SD obtained from 5 brain samples. #P < 0.05 vs. vehicle-treated SAMR1 group (t-test). *P < 0.05 and ***P < 0.001 vs. respective vehicle sham- or T2VO-SAMP8group (two-way ANOVA).

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Chinese Medicine

ISSN: 1749-8546

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