Anti-proliferative effects of raw and steamed extracts of Panax notoginseng and its ginsenoside constituents on human liver cancer cells

Table 1 Anti-proliferative effects (percentage viabilities) of raw and steamed P. notoginsen g extracts on the SNU449, SNU182 and HepG2 liver cancer cells.

P. notoginseng	SNU449		SNU182		HepG2
P. notoginseng	% viability	P value	% viability	P value	% viability	P value
Raw	80.0 (6.5)	0.018	97.1 (6.0)	0.613	100.0 (5.2)	0.974
Steamed 2 hours	81.1 (6.6)	0.019	80.2 (5.4)	0.008	82.4 (5.4)	0.013
Steamed 6 hours	75.0 (5.0)	0.003	66.6 (3.6)	<0.001	55.9 (3.2)	<0.001
Steamed 9 hours	52.5 (6.3)	<0.001	28.7 (5.1)	<0.001	47.2 (5.2)	<0.001
Steamed 15 hours	38.8 (8.2)	<0.001	26.0 (0.9)	<0.001	26.3 (4.2)	<0.001
Steamed 24 hours	17.5 (8.0)	<0.001	21.1 (2.0)	<0.001	18.9 (5.2)	<0.001

Note: The cells were exposed to the extracts at 250 μg/ml concentration. The P values are with respect to the vehicle control.

ISSN: 1749-8546