Figure 5

Relative intensities of HMG-CoA reductase (HMGCR) and low density lipoprotein receptor (LDLR) (normalized with GAPDH in Western blot experiment) after treatment of old female rats with EXD, its constituent fractions (EA, BU and WA) and premarin (PRE). The data are presented as mean ± standard deviation (SD), n ≥ 3. The treatment denoted with * represents P < 0.05 in unpaired t-test compared with control group. Welch's correction was made for comparison with significantly different variances. HMGCR: CTL vs EXD P = 0.0104, t = 4.556. LDLR: CTL vs EXD P = 0.0308, t = 2.979