Figure 1

Effects of DG-post-treatment on plasma enzyme activities in ISO-challenged rats. Animals were administered intraperitoneally with isoproterenol (ISO) at a dose of 200 mg/kg. Control animals received an injection of saline. DG extract was administered per oral at a dose of 4 g/kg immediately after the ISO challenge. Animals were sacrificed at increasing time intervals (2, 4, 6 hours) after ISO challenge. (A) Plasma lactate dehydrogenase (LDH), asparate aminotransferases (AST) and creatine phosphokinase (CPK) activities were measured. (B) The degree of protection against ISO-induced increases in plasma enzyme activities in DG-treated animals was estimated as described in Methods. Values are means ± SD (n = 6). * Significantly different from animals receiving saline injection without ISO; ^# significantly different from the time-matched ISO-challenged animals without DG post-treatment