Table 3 Major biofunctions of the identified proteins
Protein name | Subcellular location | Major functions |
|---|---|---|
Anti-oxidant effects | Â | Â |
hemopexin | Extracellular region | The highest binding affinity for heme, iron metabolism |
preprohaptoglobin | Extracellular region | The highest binding affinity for hemoglobin |
glutathione S-transferase alpha-4 (GSTA4) | Cytoplasm | GSH-related detoxification |
betaine-homocysteine S-methyltransferase 1 (BHMT1) | Cytoplasm | cysteine metabolism and GSH synthesis regulation |
Bckdha protein | Mitochondrion matrix | Branched-chain amino acids catabolism |
Liver amelioration | Â | Â |
dihydrofolate reductase (DHFR) | Cytoplasm | Synthesis of nucleic acid precursors |
quinoid dihydropteridine reductase (QDPR) | Cytoplasm. Synaptosome | Tetrahydrobiopterin recycle, amino acid metabolism |
glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | Cytoplasm. Nucleus. | Glucose metabolism, initiation of apoptosis |
ribonuclease UK114 | Mitochondrion. Cytoplasm. Nucleus. Peroxisome | Translational inhibition |
galectin-5 | Cytoplasm Cell surface of rat reticulocytes and erythrocytes | Erythrocyte differentiation and reticulocyte maturation |