Parameter
|
Result
|
---|
Investigated linear working range
|
5 - 100 mg/L
|
Limit of detectiona
|
6 mg/L (0.33 mg/capsulec)
|
Limit of quantitationa
|
13 mg/L (0.72 mg/capsulec)
|
Intraday precisionb
| |
Authentic sampled
|
10%
|
Standard solution
|
7.3%
|
Interday precisionb
| |
Authentic sampled
|
11%
|
Standard solution
|
8.2%
|
Recovery
|
104% (at 50 mg/L)
113% (at 20 mg/L)
|
- a Limit of detection (LOD) and quantitation were determined by establishing a separate calibration curve near LOD. The limits were calculated from the residual standard deviation of the regression line [42]
- b Precisions were expressed as relative standard deviation (%), intraday (n = 5), interday (n = 10)
- c Based on a sample weight of 0.9 g (2 capsules) in 50 mL ethanol
- d Total statins in authentic samples