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Table 2 Effects of zedoary oil and β-elemene on cell viability

From: Zedoary oil (Ezhu You) inhibits proliferation of AGS cells

Group n Cell viability
24 h 48 h 72 h
Zedoary oil
0 μg/mL 4 99.5 ± 0.9 99.8 ± 0.3 99.9 ± 0.2
1 μg/mL 4 95.8 ± 2.9 82.5 ± 2.5** 71.0 ± 7.0**
10 μg/mL 4 95.0 ± 2.3 77.1 ± 6.2** 69.2 ± 2.3**
30 μg/mL 4 81.2 ± 6.2** 74.3 ± 3.5** 58.4 ± 2.9**
60 μg/mL 4 65.3 ± 5.1** 49.5 ± 4.2** 42.5 ± 5.4**
90 μg/mL 4 47.4 ± 1.5** 19.0 ± 3.6** 16.7 ± 5.9**
100 μg/mL 4 35.4 ± 4.7** 13.7 ± 9.4** 9.8 ± 5.7**
300 μg/mL 4 14.8 ± 2.5** 5.3 ± 0.6** 2.5 ± 0.7**
β-elemene
11.5 μg/mL 3 98.2 ± 2.0 98.1 ± 10.7 91.2 ± 7.4
23 μg/mL 4 97.1 ± 5.0 89.0 ± 8.5 86.8 ± 14.4
92 μg/mL 4 94.1 ± 6.8 81.6 ± 3.1* 79.6 ± 3.5*
184 μg/mL 4 87.6 ± 2.0 60.3 ± 9.5** 70.0 ± 9.1**
368 μg/mL 4 25.1 ± 2.4** 14.0 ± 6.3** 12.0 ± 3.4**
1104 μg/mL 4 9.3 ± 1.3** 3.2 ± 0.7** 5.0 ± 4.1**
  1. AGS cells were treated with zedoary oil in Ham’s/F-12 medium containing 10% FBS for 24, 48 and 72 h. The cell viability was detected by MTT assays. *P < 0.05, **P < 0.01 vs. control cells.