Skip to main content

Advertisement

Table 2 Comparisons of the treatment (Black cohosh) and control (placebo) groups in terms of the Greene climacteric scale total and subscale scores at baseline and two follow-up time-points

From: Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial

Outcome variables Treatment (n = 42) Mean ± SD Control (n = 42) Mean ± SD Comparison of the groups
    Adjusted MD (95%CI) P Partial Eta2
Total score (0–63)      
Baseline 33.8 ± 6.4 31.1 ± 6.3 2.7 (-0.1 to 5.4) 0.059  
4 weeks 16.7 ± 7.7 22.9 ± 9.2 -7.8 (-11.1 to -4.4) < 0.001 0.21
8 weeks 8.0 ± 5.5 19.5 ± 11.0 -12.9 (-16.2 to -9.3) < 0.001 0.39
Vasomotor symptoms (0–6)      
Baseline 4.0 ± 1.7 3.5 ± 1.6 0.5 (-2.9 to 1.2) 0.22  
4 weeks 1.8 ± 2.0 2.6 ± 1.7 -1.1 (-0.4 to -1.8) 0.002 0.11
8 weeks 0.7 ± 1.6 2.4 ± 1.8 -1.9 (-1.2 to -2.6) < 0.001 0.26
Psychiatric symptoms (0–33)      
Baseline 18.8 ± 4.8 18.8 ± 4.3 0.1 (-2.1 to 1.9) 0.92  
4 weeks 10.8 ± 5.0 13.3 ± 6.4 -2.6 (-0.3 to -4.9) < 0.001 0.16
8 weeks 4.2 ± 3.5 11.4 ± 7.4 -7.3 (-9.6 to -5.0) < 0.001 0.31
Physical symptoms (0–21)      
Baseline 7.7 ± 3.5 6.6 ± 2.7 1.1 (-0.3 to 2,5) 0.10  
4 weeks 3.1 ± 2.3 4.7 ± 2.8 -2.0 (-3.1 to -1.0) < 0.001 0.06
8 weeks 1.4 ± 1.5 3.7 ± 2.4 -2.5 (-3.3 to -1.7) < 0.001 0.33
Loss of interest in sex (0–3)      
Baseline 2.6 ± 0.8 2.4 ± 1.4 0.2 (-0.7 to 0.3) 0.47  
4 weeks 1.8 ± 1.0 1.9 ± 1.0 -0.37 (-0.72 to -0.03) 0.03 0.06
8 weeks 1.6 ± 1.1 1.9 ± 1.0 -0.52 (-0.89 to -0.15) 0.006 0.09