Figure 5

Effect of caspase inhibitors on CK- induced HK -1 cell death. HK-1 cells were pretreated with or without different concentrations of caspase cocktail inhibitor (CI) for 2 h followed by 24 h of CK (15 μM) treatment in 1% FBS supplemented RPMI 1640 medium. The cell viability was determined by MTT assay and expressed in percentage of solvent (DMSO) control. Results were presented as mean ± SD from three independent experiments.