Figure 4From: Cratoxylum formosum (Jack) Dyer ssp. pruniflorum (Kurz) Gogel. (Hóng yá mù) extract induces apoptosis in human hepatocellular carcinoma HepG2 cells through caspase-dependent pathwaysActivation of caspase-3/7, -8 and -9 in the HepG2 treated with the CF extract. Relative luminescent units (RLU) of (A) caspase 3/7, (B) 8 and (C) 9, respectively, after HepG2 cells exposed to CF extract at various concentrations for 12 (for caspase 8, 9) and 24 (for caspase 3) h. (D), (E), and (F) represent the caspase 3/7, 8, 9 activity after being treated with CF extract (120 μg/mL) at various points. Values represent a mean ± SD, based on triplicates. *P < 0.05, **P < 0.001 significantly different from untreated cells.Back to article page