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Table 1 Ontologies of frankincense and sandalwood essential oils-regulated genes in J82 cells

From: Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer cells: a microarray and bioinformatics study

Ontology

Genes specifically regulated by frankincense essential oil

Genes commonly regulated by frankincense and sandalwood essential oils

Genes specifically regulated by sandalwood essential oil

Transcription factor activity

AHR, CEBPD, FOS, MXD1, NFAT5, RAXL1

ATF3, BHLHB2, DDIT3, EGR1, FOSB, JUN, JUNB, KLF10, KLF2, KLF4, MYC, TSC22D1

CEBPB, CITED4, DSCR1, ENO3, HES1, HLX1, ID1, ID2, ID3, IRF1, KLF5, KLF6, NFIL3, SIX4, SMAD7, TTRAP, ZNF131, ZNF165, ZNF175, ZNF18, ZNF256, ZNF483

(1.90E-05 - 5.70E-04)

   

Histone core

HIST1H3D

HIST1H2AC, HIST1H2AM, HIST1H2BF, HIST1H4E, HIST2H2AA3, HIST2H2AC

 

(3.30E-07 - 4.50E-05)

   

Negative regulation of biological process

BIRC3, HSPA1B, NFKBIL2, NUAK2, SPTBN1, UHMK1

BHLHB2, CDKN1A, DDIT3, DDIT4, EGR1, FOSB, HES1, ID1, IL1A, IL6, IL8, JUN, KLF10, KLF4, MYC, PIM1, RGS2, TNFAIP3, ZFP36

ANGPTL4, CEBPB, DLC1, ENO3, GADD45A, HMOX1, ID2, ID3, IER3, ING5, IRF1, LEP, MCL1, PMP22, PPP1R15A, PTHLH, TRIM13

(8.00E-06 - 4.50E-07)

   

Apoptosis

AHR, BIRC3, HSPA1B, NGFRAP1, NUAK2, NUDT2, PRKDC

AXUD1, CDKN1A, DDIT3, DDIT4, IL1A, IL6, PHLDA1, PIM1, SGK, TNFAIP3

ANGPTL4, C8orf4, CASP6, CEBPB, GADD45A, GADD45B, HMOX1, ID3, IER3, MCL1, PMAIP1, PPP1R15A, ZMAT3

(4.60E-04 - 1.70E-04)

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