Table 4 Cytotoxicities of the B. marginatum extracts (IC 50 values; μg/ml) after 24 h of incubation
From: Anti-infective and cytotoxic properties of Bupleurum marginatum
Cell lines | Methanol extract (μg/mL) | Dichloromethane extract (μg/mL) | P1value |
|---|---|---|---|
Caco-2 | 108.44 ± 11.43 (P* = 0.012) | 56.81 ± 6.30 (P* = 0.009) | 0.0011 |
CCRF-CEM | 22.75 ± 2.76 (P* = 0.014) | 12.54 ± 1.87 (P* = 0.004) | 0.0335 |
CCL-81 | 307.51 ± 13.76 (P* = 0.007) | 72.81 ± 6.15 (P* = 0.013) | 0.0016 |
COS-7 | 576.0 ± 11.65 (P* = 0.009) | 67.40 ± 2.76 (P* = 0.021) | 0.0019 |
HL-60 | 100.88 ± 4.02 (P* = 0.021) | 35.07 ± 2.28 (p* = 0.007) | 0.0026 |
MIA PaCa-2 | 22.51 ± 2.98 (P* = 0.023) | 14.98 ± 1.09 (P* = 0.018) | 0.0388 |
MCF-7 | 91.18 ± 8.99 (P* = 0.011) | 51.00 ± 5.20 (P* = 0.041) | 0.0279 |
PANC-1 | 34.81 ± 3.01 (P* = 0.031) | 27.62 ± 2.96 (P* = 0.022) | 0.0281 |