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Table 1 Serum biochemical parameters of different experimental groups on paracetamol (PCM) induced hepatotoxicity in mice

From: Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice

Group (n = 10) ALT (U/L) ALP (U/L) AST (U/L) Triglyceride (mmol/L)
1 61.23 ± 5.57* 85.67 ± 2.32* 145.20 ± 15.15* 2.33 ± 0.64*
2 123.94 ± 7.25 104.44 ± 2.31 368.76 ± 9.83 3.44 ± 0.56
3 72.44 ± 8.23* 81.75 ± 1.51* 250.46 ± 11.14* 2.11 ± 0.24*
4 45.44 ± 2.63* 85.83 ± 2.55* 172.64 ± 10.58* 2.53 ± 1.11*
5 76.53 ± 4.15* 91.83 ± 1.25* 235.96 ± 13.19* 2.63 ± 1.06*
6 45.26 ± 7.59* 75.75 ± 1.77* 184.03 ± 28.88* 1.99 ± 0.46*
7 74.31 ± 7.35* 85.75 ± 2.88* 239.33 ± 28.24* 2.83 ± 0.69*
  1. Values are expressed as mean ± SD where *indicates that the values are significantly difference from paracetamol control group, P < 0.05.
  2. Group1: normal mice; group 2: paracetamol control (250 mg/kg PCM + PBS); group 3: positive control (250 mg/kg PCM + 50 mg/kg silybin); group 4: acetic acid control (250 mg/kg PCM + 2 mL/kg synthetic vinegar; group 5: acetic acid control (250 mg/kg PCM + 0.08 mL/kg synthetic vinegar; group 6: 250 mg/kg PCM + 2 mL/kg pineapple vinegar; group 7: 250 mg/kg PCM + 0.08 mL/kg pineapple vinegar.