Effects of chrysin on hypoxia-induced ROS generation in cultured PASMCs. (A) Representative images of ROS fluorescence in different groups. (B) Levels of intracellular ROS, as shown by DCF fluorescence intensities. (C) Levels of MDA. Data are means ± SD from three independent experiments. Statistical analysis was performed with one-way ANOVA followed by the Newman–Student–Keuls test for multiple comparisons. ROS: reactive oxygen species; MDA: malondialdehyde; DPI: diphenyleneiodonium chloride.