Figure 4From: Bufothionine induced the mitochondria-mediated apoptosis in H22 liver tumor and acute liver injury Establishment of H 22 tumor -bearing mice model. H22 cells were injected into the abdominal cavity of a mouse. After several days, ascites occurred (A). Ascites fluids were injected into the right flank of each mouse. After several days, tumor developed under the right flank (B). Mice without inoculation did not develop tumors (C).Back to article page