Figure 6
From: Bufothionine induced the mitochondria-mediated apoptosis in H22 liver tumor and acute liver injury
Effects of drugs on tumor histology for H 22 tumor -bearing mice. Normal saline were administrated to normal rats (A).5-Fu (B), cinobufacini injection (5.14 mL/kg) (C) and bufothionine (8.02 mL/kg) (D) were respectively administrated to H22 tumor-bearing mice. After 10 days, rats were sacrificed and tumors were removed. The tissues were dehydrated, embedded, sliced and stained with HE staining for observation.