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Fig. 2 | Chinese Medicine

Fig. 2

From: Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophages

Fig. 2

PNFS suppressed NO overproduction in LPS-stimulated RAW264.7 macrophages. a PNFS decreased LPS-stimulated NO overproduction in culture supernatants. b PNFS reduced LPS-stimulated intracellular NO level. c PNFS had no scavenging effect on NO2 in vitro. Data in Fig. 2a, b and c were all expressed as the mean (SD) of 3 independent experiments. One-Way ANOVA test was used to analyzed the data and the results were F = 227.437; P < 0.001, F = 345.932; P < 0.001 and F = 599.919; P < 0.001, respectively. Then, data in Fig. 2a, b and c were all counted by SNK and LSD multiple comparisons to determine the statistical difference between two groups. The P values represented the statistical differences between each group and the corresponding positive control (without PNFS and with LPS or NaNO2 treated). *** means P <0.001

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