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Fig. 3 | Chinese Medicine

Fig. 3

From: Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophages

Fig. 3

PNFS suppressed the gene overexpression of IL-6, but exerted no influence on TNF-alpha in LPS-stimulated RAW264.7 macrophages. a, b PNFS reduced LPS-stimulated IL-6 overproduction and IL-6 mRNA overexpression in RAW264.7 macrophages. c, d PNFS exerted no influence on LPS-stimulated TNF-alpha overproduction and TNF-alpha mRNA overexpression in RAW264.7 macrophages. Data in Fig. 3a, b, c and d were all expressed as the mean (SD) of 3 independent experiments. One-Way ANOVA test was used to analyzed the data and the results were F = 766.150; P < 0.001, F = 124.746; P < 0.001, F = 212.919; P < 0.001 and F = 7.939; P = 0.001, respectively. Then, data in Fig. 3a, b, c and d were all counted by SNK and LSD multiple comparisons to determine the statistical difference between two groups. The P values represented the statistical differences between each group and the corresponding positive control (without PNFS and with LPS treated). ** means P < 0.01 and *** means P < 0.001

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Chinese Medicine

ISSN: 1749-8546

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