Fig. 7From: Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophagesPNFS did not activate LPS-stimulated PI3K/Akt signaling pathway in RAW264.7 macrophages. a PNFS had no effect on PI3K production in LPS-stimulated RAW264.7 macrophages. b PNFS had no effect on P-Akt (Thr308) production in LPS-stimulated RAW264.7 macrophages. Data in Fig. 7a and b were both expressed as the mean (SD) of 3 independent experiments. One-Way ANOVA test was used to analyzed the data and the results were F = 0.999; P = 0.422 and F = 0.157; P = 0.858, respectively. Then, data in Fig. 7a and b were both counted by SNK and LSD multiple comparisons to determine the statistical difference between two groups. The P values represented the statistical differences between each group and the corresponding positive control (without PNFS and with LPS treated)Back to article page